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Alchemists were magical practitioners that had a wide range of capabilities and powers, often imbibing or applying magic to metallurgy and/or stonework.
- Ancient alchemists had forged magical bracelets that kept captive demons from escaping arenas for Octavian matches. Their bracelets were so extremely powerful that they instantaneously disintegrated any demon regardless of the demon's strength, resistance and resilience.
- The Watchers Council employed alchemists. Smith appeared to imply such alchemists were capable of creating, transforming, or acquiring enormous riches.
- Comte de Saint-Germain was an alchemist capable of cursing a vampire into a stone statue.