Gnomes were a species of supernatural beings resembling diminutive humans.
- When Buffy Summers and her college roommate Kathy Newman came into conflict, Buffy left a wad of chewing gum on Kathy's desk, causing a book to get stuck to the desk. Buffy sarcastically said it was a gnome who caused it.
- Anya Jenkins bought the Urn of Osiris from a Desert Gnome who lived in Cairo.
- During the Fall of Los Angeles, one of these creatures was a Silver Lake resident alongside Lorne.
- Trafalgar was recruited by Rupert Giles in order to break through the energy barrier protecting the estate of Lady Genevieve Savidge.