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- "Hi, this is Fred. I mean, Practical Science Department, this is the head...Fred. How may I help you?"
- ―Winifred Burkle[src]
The Practical Science Division was a department of Wolfram & Hart charged with scientific research. Fred Burkle became head of the department after the former Angel Investigations team took over Wolfram & Hart in LA. Knox was one of the star employees of the Practical Science Division under this regime.