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A Talisman was an object, usually a piece of jewelry, enchanted by magic, giving it mystical properties which could be employed by the user.
- Sweet's talisman was used by Xander, and accidentally summoned Sweet. 
- The Tedarka Talisman was a powerful mystical artifact. It has magical energies which are able to focus and amplify its users own mystical energies. Unless properly controlled, it can corrupt the wearer. The Tedarka Talisman was used by Matereani extensively. The last time he used it, he resurrected the spirit of The Master.
- Symbol of Anyanka was the jeweled necklace worn by the vengeance demon Anyanka and which was the source of her powers and demon-hood.
- D'Hoffryn's Talisman was used by Willow to conjure him.
- The manifestations of deceased Sunnydale High students were kept alive by a special talisman.